- Weight loss
- Weakness or fatigue
- CNS Alterations
- Pain and Haematologic alterations
- Metabolic Alterations
- Anorexia
When a malignant tumour is in the early stages, there are often few manifestations usually once the tumour has grown to a sufficiently large size to cause one or more of the following problems
- Pressure on surrounding organs or nerves
- Distortion of surrounding tissue
- Obstruction of lumen of tubes
- Interference with the blood supply of surrounding tissues
- Interference with the organ function
- Disturbance of body metabolism
- Parasitic use of the body's nutritional supplies
Mobilization of the body's defensive responses, resulting in inflammatory changes
